Institute of Diabetes for Older People

Aiming for excellence in diabetes care

Research

Research in development

Diabetes and Frailty

In a successful 6 million euros collaborative bid to the EU Commission , IDOP and the Hospital Universatario de Getafe in Madrid, will lead a European Consortium to undertake a 4-year study exploring the relationship between diabetes and the emergence and course of frailty on older people. This randomised controlled trial will test various interventions that may reduce the impact of frailty and decrease disability. Professor Leo Rodriguez Manas of Madrid is Project Coordinator, and IDOP Director, Professor Alan Sinclair, is Scientific Coordinator for the project. The preparation phase of this project is already underway with recruitment of subjects expected to commence in June 2012.

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Educational Projects, Audit and Survey Work

An audit of DPPIV-inhibitor use in Primary Care.

DPPIV-inhibitors, such as sitagliptin, are relatively new glucose-lowering agents and are being used to treat type 2 diabetes. They appear to have the advantages of weight neutrality, a low incidence of side effects, and minimal hypoglycaemia. These characteristics make them a suitable option for treating older people with diabetes. This project, funded by Merck, Sharpe & Dohme (MSD), investigated the use of all DPPIV-inhibitors in older subjects in several primary care settings. Data from more than 300 subjects has been accumulated. A report will be available in January 2012 and it is hoped that a paper for publication will be submitted shortly afterwards.

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